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Trivia The global skin-lightening industry was worth USD 9.7 billion in 2023 and is expected to reach USD 16 billion by 2033

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Interestingly, IDO1 is closely associated with chronic inflammatory responses [61, 62] and increased IDO1 activity through upregulation, then alters the ratio between kynurenine and tryptophan [63]

Epidemiological data show that individuals in the highest IGF-1 quartile carry a modestly elevated risk for certain cancers, including colorectal, breast, and prostate [12]

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